[30] The I2 statistic of <50% indicates a low level of statistical heterogeneity, and that of 50% will be considered substantial statistical heterogeneity. [33]. In addition, Manual retrieval of articles, conference papers, ongoing experiments, internal reports, among others, to supplement electronic retrieval. Used in treatment of epidemic influenza and lung heat, symptom as fever or high fever, aversion to cold, muscular soreness, rhinostegnosis and nasal discharge, cough, headache, dry and sore throat, flushing tongue, or greasy fur of tongue. It cannot be bought over-the-counter and not recommended for self-medication. A: Chest radiograph of normal people; B: Chest radiograph of a patient with early-mid-stage COVID-19. Open the moisture-proof bag, please pay attention to prevent moisture. The clinical data of 66 early-mid-stage COVID-19 patients admitted to hospitals in Guangzhou between January 2020 and April 2020 were retrospectively analyzed. Lianhua Qingwen In 2005, Diagnosis and Treatment Scheme for Patients Infected with Avian Influenza (2005), issued by the Ministry of Health, Famous Kazakhstan journalist talks about Lianhua, New Progress in Study on Mechanism of Lianhua Qingwen Capsules for Treatment of COVID-19, TCM (Traditional Chinese Medicine) received by Cambodia for treating COVID-19 patients. Effect of Lianhuaqingwen Capsule on lung pathological injury and expression of inflammatory factors in mice induced by automobile exhaust [J]. Go and see the doctor if the symptom is not alleviated 3 days after administration. 3.Patients with common cold due to wind-cold dont apply to the product. [25]. WebLianhua Qingwen Jiaonang with Chinese Characters; As per continuing post-marketing surveillance, there is still incessant sale and distribution even through social media platforms, such as Facebook, of Lianhua Qingwen Jiaonang with Chinese characters, which were verified as unregistered by the FDA. Study on the effect of Lianhuaqingwen Granule on BALB /c mice infected with respiratory syncytial virus [J]. Second, CT scan result also shows that patients recover faster than the control group. Chinese drug Lianhua Qingwen is one of 3 treatments which are part of Chinas standard therapy for mild and moderate coronavirus patients. Please try again soon. Clinical observation shows that the total effective rate of traditional Chinese medicine is >90%.[15]. >10 to <14 years old: 3capsules x 3 times a day ( after breakfast, lunch and dinner).> 5 to <12 years old: 2 to 3 capsules x 3 times a day ( after breakfast, lunch and dinner). The composition of Lianhua Qingwen granules is consistent with the pathogenesis of the disease. In particular, theChinese herbma huang, scientifically known asEphedra sinica, is where the drug ephedrine is extracted from. It has a history of abuse by athletes due to its ability to increase energy and alertness and help weight loss. In 2011, Diagnosis and Treatment Guide for Influenza (2011), issued by the Ministry of Health WHO Director-General's opening remarks at the media briefing on. Therefore, the completeness of the evidence is not yet available. Chest radiographs. Individuals w/ cold deficiencies in spleen & stomach or w/ qi. COVID-19; Lianhua Qingwen; meta-analysis; protocol; systematic review. Data curation: Xiaolin Zhang, Di Cao, Qi Zhang, Junnan Liu. Lianhua Qingwen combined with conventional antiviral Western Medicine may be a useful treatment for prediabetes. To add, theonline sale and distribution ofthis productis prohibited and those engaging in this activityviolatethe R.A.10918orPhilippine Pharmacy Act. [Administration and Dosage] We first used Rhubarb to cure the disease, dredge the internal organs and relieve the heat, and then made Huoxiang fragrant and moistening. Click to view Lianhua Qingwen detailed prescribing information Overdosage View Lianhua Qingwen Experimental study on the prevention and treatment of FM1 infected mice by Lianhuaqingwen capsule [J]. For oral use after meals,4 capsules one time and thrice daily. For oral use after meals,4 capsules thrice daily or by medical ordor5 boxes for a treatment The Daily Guardian is a renascent Iloilo-based publishing firm and media outfit with bureaus in Kalibo, Boracay, Roxas, Bacolod, Antique, Guimaras, and Manila. In addition, it can also interact with other compounds and herbs. It is also for prevention of low blood pressure during anesthesia. Among the many commonly used TCMs, the most commonly used one is Lian-Hua Qing-Wen Granule (LHQWG). Accessibility Lianhua Qingwen It is approved by HSA asan over-the-counter traditional Chinese medicine to treat influenza and colds. National Library of Medicine LHQW is not approved by Singapore's HSA for the prevention and treatment of Covid-19. 1. The Authors. Keywords: 2018;Beijing: Science and Technology Literature Press, 13271329. 6.Patients with fever over 38.5 , should go to the hospital. N Engl J Med 2020;382:92936. Asia's one-stop resource for medical news, clinical reference and education, Philippine Archipelago International Trading, Click to view Lianhua Qingwen detailed prescribing information. Bioinform Biol Insights. Traditional Chinese medicine, such as Lianhua Qingwen, has achieved some curative effect in many countries, but its effect is not clear. Avoid prolonged use. How to take it to realize the maximal efficacy? [10]. Lianhua Qingwen Capsule for pneumonia In 2018, Diagnosis and Treatment Scheme for Influenza (2018), issued by the National Health and Family Planning Commission This product should not be used in treatment of wind-cold. National Health and Family Planning Commission of the people's Republic of China. The .gov means its official. Zhong said that, according to the experiment,the Lianhua Qingwen Jiaonang capsule can weakly inhibit the virus and repair cell injuries and inflammation caused by the virus. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. However, there are individual differences in the efficacy of traditional Chinese medicine compound Lianhua Qingwen, which makes the quality of evidence of clinical efficacy of traditional Chinese medicine low. Manufacture address: No.238 Tianshan street, New and high development area, Shijiazhuang, Hebei, China. The conclusion of this review will provide evidence to judge whether Lianhua Qingwen combined with Conventional antiviral Western Medicine is an effective and safe intervention for COVID-19. 2.Its not appropriate to take nourishing chinese medicine wihte taking medicine. In comparison with the control group, 1) the total effective rate was significantly higher in the observation group (P<0.05); 2) the disappearance rates of fever, cough and fatigue were statistically higher in the observation group; 3) the treatment time was significantly shorter and patient recovery was significantly better in the observation group; 4) the laboratory index levels [white blood cell (WBC), interleukin-6 (IL-6), serum amyloid A (SAA)] were better in the observation group. The effect of Lianhuaqingwen Capsule on the expression of inflammatory factors and connexin in lipopolysaccharide induced acute lung injury mice [J]. Methods: [Description]Capsules, containing tan to brown granule and powder; odour, slightly aromatic; taste, slightly bitter. Pharmacological experiments have indicated that a high dosage of Lianhua Qingwen alters the effectiveness of cyclooxygenase-2 in the arachidonic acid metabolic pathway and Nausea, diarrhea, vomiting, abdominal pain, dry mouth, rash, itching, dizziness. (4) intervention characteristics: Lianhua Qingwen in the treatment group (dosage form, dose, frequency, duration). BMJ 2008;336:9246. Consult with doctors or pharmacists before administration if other medicines are received during this time. Experimental study of Lianhuaqingwen capsule against influenza A virus in vitro [J]. Forsythiae Fructus, Lonicerae Japonicae Flos, Ephedrae Herba (processed with honey), Armeniacae Semen Amarum (stir-baked), Gypsum Fibrosum, Isatidis Radix, Dryopteridis Crassirhizomatis Rhizoma, Houttuyniae Herba, Pogostemonis Herba, Rhei Radix et Rhizoma, Rhodiolae Crenulatae Radix et Rhizoma, l-Menthol, Glycyrrhizae Radix et Rhizoma. [Administration and Dosage]For oral administration, 4 capsules once, 3 times daily. Use left/right arrows to navigate the slideshow or swipe left/right if using a mobile device. Journal of Central South University for Nationalities: Natural Science Edition 2012;31:204. [22]. A: Before treatment; B: After treatment. Infants / children aged below 4 years are not recommended to consume. It has been recommended as a recommended drug for the diagnosis and treatment of pneumonia caused by a new coronavirus (which has been included in the fifth, sixth, and seventh edition of the diagnostic and therapeutic plan version). If substantial heterogeneity is identified, we will report it and explore possible causes using sensitivity analysis and subgroup analysis. https://news.cgtn.com/news/2020-04-16/Beijing-approves-TCM-drugs-for-COVID-19-PJWgGfRAQg/index.html. Lianhua Qingwen prescription for Coronavirus disease [8]. Wang DC, Yu M, Xie WX, Huang LY, Wei J, Lei YH. Lianhua Qingwen Jiangnan (LHQW) for Flu and Colds China's top respiratory expert, the leader of the high-level expert group of the National Health Commission, Zhong Nanshan said in a webinar with overseas Chinese students, Lianhua Qingwen capsule has been proven effective for the treatment of virus. Lianhua Qingwen, which was approved by China Food and Drug Administration (CFDA) in 2004, was the first traditional Chinese medicine that entered the rapid drug approval channel of the CFDA and was used to prevent severe acute respiratory syndrome (SARS). The abstracts of all studies will be independently screened by the review authors (XLZand QL). Lianhua Qingwen (LHQW), a Chinese supplement approved by thePhilippine Food and Drug Administration (FDA) for mild Covid-19 symptoms,continues togain popularity and controversy. Excluded from the meta-analysis are duplicated publications; the control group also used traditional Chinese medicine intervention, studies with unavailable or incorrect data, articles not reporting outcomes of interest. Therefore, it is essential to perform a systematic review and meta-analysis to assess the effect of Lianhua Qingwen combined with conventional antiviral Western Medicine in clinical treatment of COVID-19 or asymptomatic infection. [Functions and Indications] According to the Cochrane Handbook bias risk assessment tool, bias risk is independently assessed. [35]. All tests are 2-tailed, and P < .05 is considered statistically significant. As a drug, ephedrine is a decongestant and bronchodilator. Traditional Chinese medicine Lianhua Qingwen treating corona virus disease 2019(COVID-19): Meta-analysis of randomized controlled trials. [59] In the early stage, there is no specific medicine or vaccine; the intervention of Chinese traditional medicine compound Lianhua Qingwen and other traditional Chinese medicine have played an important role. The Chinese embassy likewise advised the public to only purchase and consume authentic traditional Chinese medicine produced by qualified pharmaceutical manufacturers. Medicine (Baltimore). Wenwen Cui, Xin Jin, Yanfen Zhang, et al. Risk ratio (RR) was used to express the severe conversion rate and CT improvement rate absorption rate; mean difference (MD) was used to express the time of fever reduction in secondary indexes; Odds Ratio (OR) was used to express clinical efficiency and symptom disappearance rate. Buy more and get more. We will judge the each domain as low risk of bias, high risk of bias," or uncertain risk of bias" according to Higgins (2011), and pay particular attention to the risk of bias of cluster-randomised trials. [Contraindications]Those who are allergic to this product and its ingredients should not take it.